Parsley- Petroselinum Crispum Essay

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Introduction
Parsley, Petroselinum crispum is an herb used for a large myriad of medical conditions such as urinary tract infections, kidney stones, gastrointestinal disorders, constipations, jaundice, flatulence, indigestion, colic, diabetes, bronchitic cough, asthma, oedema, osteoarthritis, anemia, hypertension prostate and spleen conditions (1, 2). Parsley contains volatile oils, carotenoids, vitamins B1, B2, C and K (1, 2). The volatile oil component could be further broken down into apiole, myristicin, furanocaumarins, phenyl propanoids, phanthalides, tocopherol, ascorbic acid and various terpenoic compounds (1, 3-5). The volatile oil compounds allow parsley to induce a range of medical effects such as antimicrobial, antirheumatic,
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Inhibition of the Na+-K+ transporter pump in the kidney is the primary aquaretic effect that is associated with parsley. The mechanism of action of parsleys is mediated by the inhibition of the Na+-K+ transporter pump causes a decrease in potassium ion secretion as well as reducing sodium and potassium ions reabsorption (6, 7). Since more sodium and potassium ions are retained within the lumen of the kidney tubules over time with Na+-K+ transporter pump inhibition (7). Since sodium and potassium ions reabsorption is reduced, osmotic water flow into the lumen increases which eventually leads to the observed diuretic effect (7). This mechanism of action is further supported by a follow up experiment with amiloride, furosemide, and absence of sodium or potassium ions in testing buffers correspondingly. The supporting experiment suggested that the diuretic effect is mediated by potassium ions retention but not sodium ions, as the absence of sodium ions did not prevent the diuretic effect of parsley (7).
The following experiment aims to investigate the impacts of parsleys on renal flow and diuresis. By understanding how a diuretic agent impacts on electrolyte levels and how their effects relate in a patient, renal disorders can be further understood and treated with appropriate treatments befitting their pathophysiology.
Method
The experiment was

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