What is Pharmacology? Essay
So, what are drugs and what exactly do they do? Drugs, also known as narcotics, are chemicals that alter functions of living organisms. They are generally given for the diagnosis, prevention, control or cure of disease. They can affect the body in a negative and, or positive way. For example, have you ever taken Tylenol for a headache or migraine, but, after taking it had some adverse reaction or known side effect of the …show more content…
In order for the drug to affect you, your body first has to absorb it. Your body tends to absorb the substances more rapidly when your stomach is empty. Acidic drugs are are those that are absorbed rather quickly from the stomach while the basic narcotics are not absorbed until they reach the small intestine when administered orally or by mouth. With that being said, drugs are absorbed better by the small intestine rather than the stomach because of the larger surface area of the former.
Drugs happen to be more effective during the first pass. This means that it is the first time you have taken this drug, so it will be absorbed well by the gut wall and the liver. Once inheriting a substance one to many times, you may develop a tolerance of the drug causing you to think it may not be working, thus increasing your vascular supply, which will increase the absorption. These are all physiological factors.
Biotransformation is what makes the drug water-soluble. The highest biotransformation is located in the liver, medium biotransformation occurs in the lung, kidney and intestines. Barely any biotransformation goes on